| Customization: | Available |
|---|---|
| Type: | IVD Reagent |
| Spec: | 48T |
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The MTHFR gene encodes methylene tetrahydrofolate dehydrogenase, a rate-limiting enzyme that regulates the metabolism of folate and methionine. It plays an important role in folate metabolism, DNA methylation, and DNA synthesis. The most common polymorphism of the MTHFR gene is C677T, which locates in the catalytic domain of MTHFR, and its polymorphism leads to decreased enzyme activity and thermolability.
This product is for in vitro qualitative detection of methylenetetrahydrofolate reductase (MTHFR) gene 677 genotype in DNA extracted from human peripheral blood. Therefore, the test results of this kit provide an auxiliary diagnosis for high-risk groups with low activity of methylenetetrahydrofolate reductase.
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