| Customization: | Available |
|---|---|
| Type: | IVD Reagent |
| Spec: | 25T |
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Human Leukocyte Antigens (HLA) play a key role in the development of severe immune-mediated adverse drug reactions. Multiple phenotypically distinct immune-mediated adverse drug reactions have been associated in particular with the carriage of specific HLA class I risk alleles.
For Asians, especially the Han people, HLA-B*5801 is highly related to an allergy to allopurinol, a commonly used drug for the treatment of gout and hyperuric acid. Individuals with the genetic marker HLA-B*5801 have a much higher risk of blindness, death, and Stevenson-Jonson syndrome after taking this drug. Therefore, testing whether the HLA-B*5801 allele is carried can reduce the risk of SJS/TEN induced by allopurinol in patients.
The Tianlong Human HLA-B*5801 Gene Nucleic Acid Detection Kit is intended for the qualitative detection of the human HLA-B*5801 gene nucleic acid by Real-time Polymerase Chain Reaction (Real-time PCR) method. It can detect the human HLA-B*5801 gene in the genomic DNA of human peripheral blood samples.
Click here for more Real Time Dectection PCR kit and Related Instruments
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