Human HLA-B*5801 Gene Nucleic Acid Detection Kit-P127H

• Type: IVD Reagent
• Spec: 25T
• Transport Package: Paper Carton with Icy Bag
• Specification: 44*44*45 cm
• Trademark: Tianlong
• Origin: Suzhou
• HS Code: 3822009000
• Production Capacity: 5000000 Test/Year

Product Description

Product Description

Human Leukocyte Antigens (HLA) play a key role in the development of severe immune-mediated adverse drug reactions. Multiple phenotypically distinct immune-mediated adverse drug reactions have been associated in particular with the carriage of specific HLA class I risk alleles.

For Asians, especially the Han people, HLA-B*5801 is highly related to an allergy to allopurinol, a commonly used drug for the treatment of gout and hyperuric acid. Individuals with the genetic marker HLA-B*5801 have a much higher risk of blindness, death, and Stevenson-Jonson syndrome after taking this drug. Therefore, testing whether the HLA-B*5801 allele is carried can reduce the risk of SJS/TEN induced by allopurinol in patients.

The Tianlong Human HLA-B*5801 Gene Nucleic Acid Detection Kit is intended for the qualitative detection of the human HLA-B*5801 gene nucleic acid by Real-time Polymerase Chain Reaction (Real-time PCR) method. It can detect the human HLA-B*5801 gene in the genomic DNA of human peripheral blood samples.

Features

*Wide Coverage
Reliable detection of Human HLA-B*5801 Gene in exon 2 and exon 3

*High Sensitivity
The limit of detection is up to 1ng/μL

*Internal Control
The use of internal control system in the kit can effectively prevent false negative results

*High Precision
The precision values of intra and inter Ct values are all ≤5%

*User-friendly
Widely applicable in instruments with FAM, HEX/VIC, Cy5 fluorescence channels

*More Accessible
CE marked, accessible for more counties

 

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