Human K-ras Gene Mutation Detection Kit-P112H

• Type: IVD Reagent
• Spec: 20T
• Transport Package: Paper Carton with Icy Bag
• Specification: 44*44*45 cm
• Trademark: Tianlong
• Origin: Suzhou
• HS Code: 3822009000
• Production Capacity: 5000000 Test/Year

Product Description

Product Description

K-ras gene, located on chromosome 12p12.1, is one of the important oncogenes. Studies have shown that K-ras gene mutations exist in non-small cell lung cancer and colorectal cancer, and mutation of K-ras occurring at codon 12 and 13 which could cause KRAS protein to mutate and remain activated can render the drug ineffective.

The kit uses genomic DNA extracted from tumor paraffin-embedded tissue sections of human non-small cell lung cancer and colorectal cancer as test samples for the qualitative detection of 12 somatic mutations at codon 12 and 13 of K-ras gene.

This product is suitable for patients with non-small cell lung cancer and colorectal cancer before entering the individualized targeted therapy course and provides auxiliary diagnostic evidence for the individualized medication of clinical tumor-targeted drugs.

Features

*Wide Coverage
Reliable detection of Human K-ras gene Mutation, covering 12 somatic mutations at codon 12 and 13 of K-ras gene in a single run
 

The mutation of K-ras codon 12	The mutation of K-ras codon 13
Gly12Ser	Gly13Ser
Gly12Arg	Gly13Arg
Gly12Cys	Gly13Cys
Gly12Asp	Gly13Asp
Gly12Ala	Gly13Ala
Gly12Val	Gly13Val

*High Sensitivity
Sensitive to detect up to 1% mutation in K-raf gene

*Internal Control
The use of internal control system in the kit can effectively prevent false negative results

*High Precision
The Tm coefficient of variation was no more than 8% or Tm value difference ≤1ºC

*More Accessible
CE marked, accessible for more counties

*User-friendly
Validated on the most common qPCR machines with FAM fluorescence channel

 

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